• For tooth Pain and toothache: When you have a toothache, the pain is often caused by inflammation in the gums or the tooth’s pulp. Zerodol-SP for tooth pain works because aceclofenac and paracetamol block the pain signals, while Serratiopeptidase reduces the gum swelling, providing complete relief from the throbbing pain and discomfort.
• Relief from Joint Pain (Osteoarthritis & Rheumatoid Arthritis): Zerodol-SP is widely prescribed to manage the pain and inflammation associated with joint conditions. In osteoarthritis, it helps relieve the pain from cartilage wear and tear. In rheumatoid arthritis, it helps reduce the painful swelling and stiffness in the joints caused by the body’s immune system attacking them(Autoimmmunity).
• Back Pain, Neck Pain, and Spondylitis: For conditions such as lower back pain, a stiff neck, or ankylosing spondylitis, Zerodol-SP provides relief by reducing inflammation in the spine and relaxing the muscles.
• Post-Surgical Pain and Swelling: After a minor surgery or a dental procedure, the body’s natural response is to create inflammation and swelling at the site. The Serratiopeptidase in Zerodol-SP helps to clear away the excess fluid and proteins, reducing swelling and bruising, which in turn speeds up the healing process.
• Pain from Injuries (Sprains and Strains): For sports injuries, sprains, or muscle strains, Zerodol-SP works to alleviate the immediate pain, control the inflammation, and reduce the swelling, helping you recover more comfortably.

• If you have a known allergy or hypersensitivity to aceclofenac, paracetamol, serratiopeptidase, aspirin, or any other NSAIDs (like Ibuprofen), or any of the ingredients of this medicine.
• Do not give this medication to children. It is indicated in adults only.
• If you have a history of asthma attacks, severe skin rashes, or allergic reactions after taking other painkillers.
• If you have an active or a history of frequent stomach ulcers, or have experienced bleeding or perforation in any part of your digestive system, stomach, or intestines.
• If you are in your third trimester of pregnancy.
• If you suffer from severe heart failure, liver disease, or kidney disease

• Nausea, vomiting, or diarrhoea
• Stomach pain
• Indigestion
• Heartburn
• Loss of appetite
• Dizziness or headache

• Severe allergic reactions such as rashes, hives, difficulty breathing, or swelling of the face, lips, tongue, or throat
• Bleeding in the stomach
• Black, tarry, or bloody stools
• Coughing up blood or vomit that looks like coffee grounds
• Chest Pain
• Weakness
• Shortness of Breath
• Jaundice (yellowing of skin or eyes)
• Difficulty urinating
• Bloody urine
• Blistering, peeling, or a purple skin rash (e.g., Stevens-Johnson Syndrome)

Other General Warnings

• You have a history of liver, kidney, or heart conditions.
• You have high blood pressure, asthma, or any bleeding disorders.
• You have a history of stomach ulcers, acidity, or inflammatory bowel disease (like Crohn’s disease).
• You are scheduled for any surgery, including dental surger

• The standard dose of Zerodol-SP tablet is one tablet. Take it once or twice a day as prescribed by your doctor.
• Always take this medicine with food and a full glass of water. This is crucial for protecting your stomach lining from irritation.
• Swallow the tablet whole. Do not crush, chew, or break it, as this can affect how the medicine is released into your body.
• Maintain a consistent time gap between doses as advised by your doctor.
• Use this medicine for the shortest duration necessary to control your symptoms. Do not use it for long-term pain without medical supervision.

• Store Zerodol-SP tablets in a cool, dry place at room temperature (below 30°C).
• Keep the medicine in its original strip or container to protect it from direct sunlight and moisture.
• Always ensure the tablets are stored out of the reach and sight of children and pets.
• Do not use the tablets after the expiry date printed on the packaging.
• Dispose of any expired or unused medicine responsibly.

• Always take Zerodol-SP tablet with a meal or a glass of milk to prevent stomach upset and reduce the risk of ulcers.
• Never take Zerodol-SP with other painkillers containing paracetamol or other NSAIDs (like Ibuprofen), as this can lead to an overdose and serious side effects.
• Avoid drinking alcohol while on Zerodol-SP tablet to protect your stomach and liver.
• Zerodol-SP is very effective for toothaches, but it only treats the symptoms, not the underlying cause. You should see a dentist to address the underlying dental issue.
• If you are taking this medicine for more than a few days, your doctor may want to monitor your kidney and liver function.
• Zerodol SP can be used to treat the pain, inflammation, and fever associated with tonsillitis; however, it is a prescription medication that should be taken only as directed by a physician. It is not an antibiotic and will not treat an underlying bacterial infection if present.
• Zerodol SP should be taken exactly as prescribed by your doctor at the recommended best time for you (morning, afternoon, or night). It may be taken on an empty stomach, before food, or after/meal, as advised. Ensure you follow your routine and complete the full course. Your doctor provides the schedule to ensure the medicine works effectively.

Overdose

Missed a Dose

• Zerdol‑SP (aceclofenac + paracetamol + serratiopeptidase) works through a complementary triple mechanism: aceclofenac inhibits cyclo‑oxygenase (COX) enzymes, thereby decreasing inflammation and pain at the site of injury; paracetamol acts via its analgesic and antipyretic effects with minimal peripheral anti‑inflammatory action; and serratiopeptidase, breaks down inflammatory proteins and exudates at the affected site, reducing swelling and promoting tissue healing, together providing effective relief of pain, inflammation, and oedema.
• Serratiopeptidase is a unique enzyme that helps clean up the mess left behind by an injury. When tissues are damaged, your body can produce a lot of inflammatory proteins and fluid debris that causes swelling. Serratiopeptidase breaks down this inflammatory proteins and fluid debris allowing the trapped fluid to drain away and reducing the pressure and swelling. This speeds up the entire healing process.
• Together, these three ingredients provide powerful relief by blocking pain signals, reducing inflammation, and actively cleaning up the debris that causes swelling.

Interactions with other drugs