• If you are allergic to metformin, glimepiride or any of the ingredient of Dailyglim M Forte Tablet.
• If you are pregnant or breastfeeding.
• If you have serious kidney failure or liver failure.
• If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma
• If you have dehydration, severe infections, shock and injections containing iodine
• If you have had heart or lung failure, recent incidence of heart attack and shock
• If you are alcoholic.

• Nausea
• Vomiting
• Diarrhoea
• Abdominal pain
• Loss of appetite
• Metallic taste
• Headache
• Hunger pangs
• Sleepiness
• Restlessness

Other General Warnings

• You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar.
• You are going to have a diagnostic imaging test which involves injection of iodine.
• You have dehydration due to diarrhoea, vomiting or limited fluid intake.
• You have a planned surgery.
• You have serious kidney and liver problems.
• You have thyroid disorder.
• You are overweight (specific diet restriction may be suggested).
• Long term use of this medicine can cause low level of vitamin B12, which may result in tingling, pins-and-needles sensation, numbness and weakness.

• Store at room temperature in a dry place. Protect it from light and moisture.
• Keep out of the reach of children and pets.

• Take Dailyglim-M 2 Forte Tablet PR exactly as prescribed by your doctor.
• Take with meals, preferably with your first meal of the day, at the same time daily.
• Do not skip doses or change the dosage without consulting your doctor.
• Maintain a healthy diet and exercise regularly to support treatment.
• Monitor blood sugar levels regularly to track effectiveness.
• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Report any side effects, such as dizziness, nausea, or low blood sugar, to your doctor.
• Avoid excessive alcohol and sugary foods while taking this medicine.

Overdose

• Overdose of Dailyglim M Forte Tablet may lead to severe hypoglycemia (low blood sugar) and lactic acidosis (excessive lactic acid build-up). This can result in headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, low mood, confusion, dizziness etc.
• If you experience these, immediately take glucose or juice or sugar-containing products (Sugar candy).
• Contact your doctor immediately or visit the nearest hospital as you may require close monitoring for the next few hours.

Missed a Dose

• Missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, fruity smell from breath etc.
• If you missed any dose of medicine, take it as soon as you remember. If it’s time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

• Glimepiride lowers the blood sugar level by increasing release of insulin hormone from pancreas. Insulin moves sugar (glucose) from the blood into the cells.
• Metformin decreases the absorption in the intestine and production of sugar by the liver.
• Both of these components are known to increase the insulin sensitivity of the body (allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Interactions with other medicines

• Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Especially if you are taking medicines to treat high blood pressure, heart failure, high/abnormal cholesterol levels, blood thinners, anti-infectives, thyroid medicine anti-diabetics, anti-asthmatics, oral contraceptives, pain killers, immunomodulatory medicines or medicines for the brain-related disorder.
• Medicines used for acidity like ranitidine, anti-hypertensive medicine like atenolol, propanolol, clonidine and anti-pyschotic medicine like reserpine can either increase or decrease the effect of this medicine, thus masking the signs of low blood sugar, thus should be cautious.

Interactions with food items

• Take Dailyglim-M 2 Forte Tablet PR with meals to reduce stomach upset and improve effectiveness.
• Avoid consuming excessive sugary foods and drinks, as they can raise blood sugar levels.
• Limit alcohol intake, as it may increase the risk of low blood sugar (hypoglycemia) or affect liver function.
• Avoid skipping meals while on this medicine to prevent sudden drops in blood sugar.
• Maintain a balanced diet rich in fiber, vegetables, and whole grains to support blood sugar control.
• Be cautious with high-carb snacks, as they can interfere with optimal blood sugar management.
• Discuss with your doctor before taking supplements or herbal products that may affect blood sugar levels.